Supported by Simons Foundation, Scientists Discover Clues To Altered Brain Wiring In Autism

Tuesday, November 15, 2016

Supported by Simons Foundation, Scientists Discover Clues To Altered Brain Wiring In Autism

Autism is an agonizing puzzle, a complex mixture of genetic and environmental factors.

One piece of this puzzle that has emerged in recent years is a biochemical cascade called the mTOR pathway that regulates growth in the developing brain.

A mutation in one of the genes that controls this pathway, PTEN (also known as phosphatase and tensin homolog), can cause a particular form of autism called macrocephaly/autism syndrome...

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