Michael J. Fox Foundation Awards $24 Million in Research Grants

Thursday, February 28, 2019

Michael J. Fox Foundation Awards $24 Million in Research Grants

The Michael J. Fox Foundation for Parkinson's Research (MJFF) has announced a hundred and twenty-seven grants totaling $24 million in support of research focused on defining, measuring, and treating Parkinson's disease.

In support of defining and understanding the causes of Parkinson's, the foundation awarded thirty-two grants totaling more than $5.3 million. In partnership with the Silverstein Foundation for Parkinson's with GBA, the grants included support for sixteen projects focused on investigating the biology, biomarkers, and therapies related to the GBA (glucocerebrosidase) pathway. According to MJFF, mutations in the GBA gene are the most common genetic factor in Parkinson's disease. The foundation also is providing support for a similar funding program associated with alpha-synuclein, a protein that lumps in the cells of people with Parkinson's.

In addition, the foundation awarded sixty-three grants totaling nearly $8.7 million in support of efforts to measure the progression of the disease and assess the effectiveness of treatments. The grants include support for researcher Matthew Cooper, who is working to develop an imaging tracer of the protein NLRP3, which is involved in inflammation...

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